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This may lead to the induction of cell cycle arrest and apoptosis in susceptible tumor cells
InChi: InChI=1S/C28H41N5O6S/c1-4-10-24(33(38)19-34)22(17-20(2)3)25(35)31-23(26(36)32-27-29-15-16-40-27)13-8-9-14-30-28(37)39-18-21-11-6-5-7-12-21/h5-7
Yamamoto K
chromatin organization
SIS3 HCl - CAS# 521984-48-5 225 This may lead to theSIS3 HCl, CAS No. 521984 48 5, a novel specific inhibitor of Smad3, inhibits TGF and activin signaling by suppressing Smad3 phosphorylation without affecting the MAPK p38, ERK, or PI3 kinase signaling pathways. Product information CAS Number: 521984 48 5 Molecular Weight: 489. 99 Formula: C28H28ClN3O3 Synonym: (E) SIS3 Chemical Name: (2E) 1 (6,7 dimethoxy 1,2,3,4 tetrahydroisoquinolin 2 yl) 3 {1 methyl 2 phenyl 1H pyrrolo[2,3 b]pyridin 3 yl}prop 2 en
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