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InChi: InChI=1S/C22H26N2O7/c25-17-12-11-15(20(28)23-17)24-21(29)14-8-7-9-16(19(14)22(24)30)31-13-6-4-2-1-3-5-10-18(26)27/h7-9
PMCID: PMC6794838
SGC707 was used at 5-10 µM final concentration in various in vitro assays
or with a dose of 2 mg/kg orally every 48 h for 2 months
Doramapimod Catalog No.:M10899-2 InChi: InChI=1S/C22H26N2O7/c25-17-12-11-15(20(28)23-17)24-21(29)14-8-7-9-16(19(14)22(24)30)31-13-6-4-2-1-3-5-10-18(26)27/h7-9Doramapimod, also known as BIRB 796, is a member of the N pyrazole N' naphthly urea class of p38MAPK inhibitors, which binds to the kinase with both slow association and dissociation rates. BIRB 796 has entered clinical trials for the treatment of autoimmune diseases. Product information CAS Number: 285983 48 4 Molecular Weight: 527. 66 Formula: C31H37N5O3 Chemical Name: 3 [3 tert butyl 1 (4 methylphenyl) 1H pyrazol 5 yl] 1 {4 [2 (morpholin 4