Danusertib (PHA-739358) Catalog No.:M7725-10 Epub 2017 Dec 28

Name: Danusertib (PHA-739358) Catalog No.:M7725-10 Epub 2017 Dec 28
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Description

Epub 2017 Dec 28

YCN47284 was first reported in WO 9621450

RG3039 (PF-06687859

2014 Nov 7

Danusertib (PHA-739358) Catalog No.:M7725-10 Epub 2017 Dec 28Danusertib, also known as PHA 739358, is a small molecule 3 aminopyrazole derivative with potential antineoplastic activity. Aurora kinase inhibitor PHA 739358 binds to and inhibits the Aurora kinases, which may result in cell growth arrest and apoptosis in tumor cells in which Aurora kinases are overexpressed. This agent may preferentially bind to and inhibit Aurora B kinase. Aurora kinases, a family of serine threonine kinases, are important

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