Allopregnanolone Catalog No.:M22067-C Smiles: CC[C@H](CO)NC1N=C2C(N=CN2CCC)=C(NCC2C=CC=CC=2)N=1

Smiles: CC[C@H](CO)NC1N=C2C(N=CN2CCC)=C(NCC2C=CC=CC=2)N=1

The EC50 value for Pimodivir are 8 and 12 nM for A(H1N1) and A(H3N2) strains

InChi: InChI=1S/C23H32N6/c1-15-12-16(2)21-20(13-15)27-22(28-21)19-14-25-23(26-17(19)3)24-9-5-6-18-7-10-29(4)11-8-18/h12-14

6S)-2-[(2S

Allopregnanolone Catalog No.:M22067-C Smiles: CC[C@H](CO)NC1N=C2C(N=CN2CCC)=C(NCC2C=CC=CC=2)N=1Allopregnanolone is a selective activator of GABA A receptor with the concentration of 10 nM . GABA A receptor is a pentameric transmembrane receptor and sits in the membrane of neuron. As a subtype of receptor for the neurotransmitter GABA, GABA A receptor mediates the bulk of synaptic inhibition in the central nervous system and prevents action potential generation by short circuiting the depolarization produced by excitatory neurotransmission. It