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Hydroxycinnamic acid as a novel scaffold for the development of cyclooxygenase-2 inhibitors
3-Carbamoyl-1-methylpyridin-1-ium chloride is an endogenous metabolite
30)31)6-7-18(16)25-20/h4-8
31(5):845-52
MK-4101 Size:Contact [email protected] for quotation Hydroxycinnamic acid as a novelMK 4101 is a Smoothened (SMO) antagonist (IC50 of 1. 1 M for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1. 5 M for mouse cells; IC50 of 1 M for KYSE180 oesophageal cancer cells). MK 4101 has robust antitumor activity that inhibits tumor cell proliferation and induces extensive apoptosis. Product information CAS Number: 935273 79 3 Molecular Weight: 493. 47 Formula: C24H24F5N5O Chemical Name: 5 (3,3 difluorocyclobutyl) 3