R-(+)-ETOMOXIR - CAS# 124083-20-1 093 It displays >200 fold selectivity

It displays >200 fold selectivity over other HDAC isoforms 1

159(6):1236-46

InChi: InChI=1S/C16H20N4O3/c1-10-14-15(17-5-7-23-8-6-21)12-9-11(22-2)3-4-13(12)18-16(14)20-19-10/h3-4

Molecular Weight: 591

R-(+)-ETOMOXIR - CAS# 124083-20-1 093 It displays >200 fold selectivityR (+) ETOMOXIR, CAS No. 124083 20 1, is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT 1) on the outer face of the inner mitochondrial membrane. This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as