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Before we begin, I am making an executive decision: Humans don't count

It has an impressive Ward ability, requiring an opponent to sacrifice a legendary artifact or legendary creature to target it with spells or abilities

While I personally think that Exocrine s ability to clear the board and possibly even finish off opponents if life totals are low enough pushes it over the top, there are a variety of useful effects to be found among these creatures

Card Name Mana Cost Type Legendary Planeswalker Karn Rarity Mythic Rare rules Text Activated abilities of artifacts your opponents control can't be activated.+1: Until your next turn, up to one target noncreature artifact becomes an artifact creature with power and toughness each equal to its mana value.2: You may reveal an artifact card you own from outside the game or choose a face-up artifact card you own in exile