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ISPA-28 thiourea (hydrochloride) GDC-0032 potently inhibits signal transduction

SKU: 26025179244

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Description

GDC-0032 potently inhibits signal transduction downstream of PI3K and induces apoptosis at low concentrations in breast cancer cell lines and xenograft models that harbor PIK3CA mutations

CAS Number: 668467-91-2

Smiles: O=C(C1=CN(CC2=CN=CN2CC2C=CC(Br)=CC=2)C=C1C1=CC=CC2=CC=CC=C21)N1CCOCC1

Clobetasol belongs to US Class I (Europe: class IV) of the corticosteroids

ISPA-28 thiourea (hydrochloride) GDC-0032 potently inhibits signal transductionISPA 28 is a specific plasmodial surface anion channel (PSAC) antagonist. ISPA 28 binds directly and reversibly to CLAG3. Product information CAS Number: 1006335 39 2 Molecular Weight: 408. 45 Formula: C21H24N6O3 Chemical Name: N (1,5 dimethyl 3 oxo 2 phenyl 2,3 dihydro 1H pyrazol 4 yl) 3 (1 ethyl 3 methyl 1H pyrazol 4 yl) 4,5 dihydro 1,2 oxazole 5 carboxamide Smiles: CN1C(C)=C(NC(=O)C2CC(=NO2)C2=CN(CC)N=C2C)C(=O)N1C1C=CC=CC=1 InChiKey: YMLINDVVJXDIRW

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